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Introduction

 

            A current dispute
surfaced in the Philippines, regarding the termination of the use of a dengue
vaccine named, Dengvaxia. This basically meant that a population of over
730,000, particularly children, was suspended from using the said vaccine as it
was reported by a French drug company Sanofi,that it could exacerbate the
disease among people who have not been afflicted by dengue in the past. By that
time, public schools in the areas of Metro Manila, Central Luzon, and CALABARZON,
carried out vaccine programs. A few days after the controversy, the World
Health Organization (WHO), clarified that they did not prescribe or advocate
the use of Dengvaxia on any parts of the world for their immunization programs.

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In most tropical countries, mosquito-borne diseases,
including dengue, malaria and filariasis has been one of the leading causes of
death. During the late 1950s, dengue
epidemics were first recognized in the Philippines and Thailand (previously
known as dengue hemorrhagic fever). The
most common victims are children younger than 10 years of age. It is a fast
emerging pandemic-prone viral disease that mainly flourishes in local
municipalities, suburbs and the countryside and kills about 20, 000 people a
year. The shocking increase of dengue incident year after year is a
concern of our local health department and the society. Due to that, various
campaigns against dengue are launched by both the public and private sectors. Commercially,
there are various products of mosquito repellents readily available for
consumers but most of them are highly made from harmful substances and expensive
making it less accessible.

 

Atis
(Annona Squamosa), a tropical plant with only a height of three or five
meters that typically grows in the Philippines yields leaves and seeds
containing a substance known as Annonaceous Acetogenins (ACGs) which are said
to have insecticidal properties. A study conducted by (Pierre Champy, 2011),
proved that statement. Moreover, the results of his study showed that
Annonaceous Acetogenins (ACGs) were toxic to insects, therefore increasing the
possibility for it to become an effective insecticide. A similar study by
(Ashok Kumar, et. al, 2010) showed that Atis (Annona Squamosa) leaves
contain active compounds, namely, essential oil, terpenes, alkaloids-anonaine,
roemerine, corydine, norcorydine, isocorydine, and norisocorydine, which
apparently contributes to its insecticidal properties.

 

As
we all know, the Philippines is a tropical country, allowing the mosquitoes to
thrive and grow in large numbers as it generates the perfect environment for
them. This is the main factor of the ever-growing problem in the country, specifically
mosquito-borne diseases such as malaria, dengue, and filariasis. The said
problem allowed the need for a natural and accessible insecticide for almost
all households in the said country. The study aims to determine the efficacy of
the said mosquito repellent (atis leaves and seeds). Furthermore, the
researchers would also like to verify whether the product is much safer and
cheaper than the commercial ones.

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